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Apply once or twice a day. The dosage may be lowered when the condition of the skin starts to improve.
This cream/ointment is intended for use on the skin only.
Corticosteroid-response inflammation, pruritis and allergic conditions of skin, where secondary bacterial infection is present.
Known hypersensitivity, fungal infections, tuberculosis of the skin, vaccinia, varicella, and herpes simplex. Should not be applied in the external auditory canal of patients with perforated eardrum. Not intended for ophthalmic use.
Ototoxicity and nephrotoxicity may be increased if the patient is being concurrently treated with an aminoglycoside antibiotic. Pregnancy and lactation, pediatrics. If sensitization or irritation occurs, discontinue use. When using gentamicin-containing preparations to control secondary infection in chronic dermatoses, it should be borne in mind that the skin is more liable to become sensitive to other substances, including gentamicin. In the presence of an infection, the use of an appropriate antifungal or antibacterial agent should be instituted. If a favorable response is not obtained, the use of this preparation should be temporarily discontinued. If extensive areas are treated or if the occlusive technique is used, the possibility exists of increased systemic absorption. Systemic absorption of topical corticosteroids has produced reversible HPA axis suppression, manifestations of Cushing’s syndrome, hyperglycemia and glucosuria in some patients. Such patients should be periodically evaluated for evidence of HPA axis suppression. Application to children should be limited to the least amount compatible with an effective therapeutic regimen.
Burning, itching, irritation, dryness,, folliculitis, hypertrichosis, acneiform eruptions, hypopigmentation, perioral dermatitis, allergic contact dermatitis, maceration of the skin, secondary infection, skin atrophy, striae, and miliaria. Signs of a sensitivity reaction to gentamicin in the form of a low-grade reddening with swelling, dry scaling or itching, or simply as a failure to heal. Allergic cross-reactions may occur which could prevent the future use of kanamycin, paromomycin and streptomycin.
Phenytoin, barbiturates, carbamazepine, aminoglutethimide, rifampicin. Thiazide and loop diuretics, cardiac glycosides, acetazolamide. Oral hypoglycemics, insulin. Antihypertensives, anabolic steroids, ophthalmic idoxuridine, NSAID.