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  • B-Six 300
    / SAM-ON

    Active Ingredient
    Vitamin B6 300 mg

    Status in Israel

    Presentation and Status in Health Basket

    Presentation Basket Yarpa Pharmasoft


    30 X 300 mg

    not in the basket chart 7150 2002


    One tablet a day.


    Pyridoxine deficiency (inadequate diet, drug induced B6 dependent convulsion, B6 responsive anemia, alcoholism).


    Known hypersensitivity to pyridoxine.

    Special Precautions

    Long-term administration of large doses (2 G or more daily) may cause pyridoxine-induced neurotoxicity, resulting in impairment of senses in distal limbs and ultimately progressive failure of muscular coordination. Following discontinuation, neurological dysfunction gradually improves. Pregnancy and lactation: Potential benefits to the mother must be weighed against the potential hazards to the fetus. Large doses of pyridoxine may result in a pyridoxine dependency syndrome in the neonate. Safety of use in breastfeeding has not been established.

    Side Effects

    Sensory neuropathic syndromes, unstable gait, numb feet, awkwardness of hands, perioral numbness, decreased sensation to touch, temperature and vibration, paresthesia, somnolence and low serum folic acid levels.

    Drug interactions

    Levodopa, cycloserine, isoniazid. Chloramphenicol, cycloserine, ethionamide, hydralazine, penicillamine, immunosuppressants, estrogens, phenobarbital, phenytoin.

    Sam-On Ltd., Israel
    Licence holder