Advil Liqui-Gels

/ Neopharm

For oral administration and short-term use only.
Adults, the elderly, and children and adolescents over 12 years of age:
If in children and adolescents, between the age of 12 and 18 years, this medicinal product is required for more than 3 days, or if symptoms worsen, a doctor should be consulted.
For adults aged 18 years or older the minimum effective dose should be used for the shortest time necessary to relieve symptoms. The patient should consult a pharmacist or a doctor if symptoms persist or worsen, or if the product is required for more than 10 days.
One or two capsules up to three times per day as required. The respective dosing interval should be chosen in line with the observed symptoms and the maximum recommended daily dose. Doses should be given approximately every 6-8 hours, with a minimum interval of 4 hours between each dose. A total dose of 1200 mg of ibuprofen [6 capsules] should not be exceeded in any 24 hour period.
The capsules should be taken with water.
Not to be used for children under 12 years of age

For the relief of pain associated with headache, toothache, backache, muscular and menstrual pains. Antipyretic. Anti-inflammatory for rheumatic diseases. For the treatment of pain associated with migraine.

Hypersensitivity to ibuprofen or any of the constituents in this product.
Ibuprofen is contraindicated in patients who have previously shown hypersensitivity reactions (e.g. asthma, rhinitis, angiodema or urticaria) in response to aspirin or other non-steroidal anti-inflammatory drugs.
Active or previous peptic ulcer (two or more distinct episodes of proven ulceration or bleeding).
History of upper gastrointestinal bleeding or perforation, related to previous NSAID therapy.
Patients with severe hepatic failure, renal failure or heart failure.
Use in last trimester of pregnancy.

ACE inhibitors, aspirin (high dose), b-blockers, clozapine, cyclosporin, digoxin, lithium, oral anticoagulants, methotrexate, midozolam, olanzapine, rifampicin, theophylline, tractolimus, warfarin.

Pregnancy: Whilst no teratogenic effect has been demonstrated in animal experiments, use of ibuprofen during pregnancy should be avoided during the first 6 months of pregnancy. During the third trimester, ibuprofen is contraindicated as there is a risk of premature closure of the foetal ductus arteriosus with possible persistent pulmonary hypertension. The onset of labour may be delayed and duration of labour increased with an increased bleeding tendency in both mother and child.
Lactation: In limited studies, ibuprofen appears in the breast milk in very low concentrations, and is unlikely to affect the breast fed infant adversely.