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  • Varicella Zoster Vaccines
    3 Drugs classified under this drug class


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    SHINGRIX
    GSK
    RX
    partial basket chart
    SHINGRIX

    Varicella Zoster Vaccines. Varicella Zoster Virus Vaccines 50 mcg/ 0.5 ml.
    50 mcg/0.5 ml
    Vials. Powder and susp. for  IM inj.1/10 X  0.5 ml
    Vaccination sched. consists of 2 doses of 0.5 mL each: an initial dose followed by    a second dose 2 months later.
     Prevent. of herpes zoster (HZ) and post-herpetic neuralgia (PHN), in
    adults 50 years of age or older and  adults 18 years of age or older at incr. risk of HZ.
    C/I: Hypersens.

    Varilrix
    GSK
    RX
    not in the basket chart
    Varilrix

    Varicella Zoster Vaccines. Varicella virus live attenuated NLT 2000 PFU.
    PWDR (+ solv. for inject): 0.5 ml (1 dose).
    S.C. in deltoid. 12 mths-12 yrs: 1 dose.
    13 yrs and over: 2 doses with interval
    of 6 wks (minimum) betw. doses. High
    risk pts: additional doses may be reqd.
    Not to be admin. intraderm. or
    intravasc.
    Active immunizat. against varicella in
    healthy pts. only from 12 mths of age.
    in individuals with severe humoral or cellular (primary or acquired) immunodef. such as:subjects with immunodefic. states with a total lymphocyte count less than 1,200 per mm3; subjects presenting other evidence of lack of cellular immune competence (e.g. leukaemias, lymphomas, blood dyscrasias, clinic. manifest HIV infect.); subjects on current or recent immunosuppressive ther. (including high doses of corticosteroids). Not contraindic. in individuals who are receiving topical or low-dose parenteral corticosteroids (e.g. for asthma prophylaxis or replacement ther.);
    severe combined immunodefic.; agammaglobulinemia;
    AIDS or symptom. HIV infect. or an age-specific CD4+ T-lymphocyte percentage in children below 12 months: CD4+ <25%; children between 12-35 months: CD4+ < 20%; children between 36-59 months: CD4+ < 15%.
    *Hypersens. incl to neomycin. but a hist. of contact dermatitis to neomycin is not a contraindic.
    *Subjects having shown signs of hypersens. after previous admin. of varicella vaccine.
    *Pregn. In addit., pregn. should be avoided for 1 month following vaccin.

    Zostavax
    MSD
    RX
    partial basket chart
    Zostavax

    Varicella Zoster Vaccines. Varicella Zoster Virus Vaccines 19,400 PFU/0.65 ml.
    PRE-FILLED SYR. (PWDR + SOLV. for INJ.):
    0.65 ml.
    S.C. a single dose (0.65 ml), prefer.
    in the deltoid region. Do not inject
    intravascularly.
    Prevention of herpes zoster (shingles) in
    pts. 50 yrs of age and older.
    C/I: Hypersens. to the product, to any of
    the excip. (e.g., neomycin);
    Primary/ acquired immunodef. states;
    Immunosuppress. ther. (incl. high-dose
    corticoster.), however, it is not C/I for use
    in pts. who are receiv. topical/inhaled
    corticoster. or low-dose syst. corticoster.
    or in pts. who are receiv. corticosteroids
    as replacem. ther. Active untreated tuberculosis; Pregn.
    and should be avoided for 1 mnth foll.
    vaccine.

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