siRNA

1 Drug classified under this drug class

siRNA. Vutrisiran 25 mg/0.5 ml.
Pre-filled syr. with  0.5 ml sol. for inj.
Recommen. dose is 25 mg admin. by SC inject. once every 3 months. Vitamin A supplement. at approx., but not exceeding, 2,500 IU to 3 ,000 IU /d is advised.
Tmt. of hered. transthyretin-mediated amyloidosis (hATTR amyloidosis) in adult with stage 1 or stage 2 polyneuropathy:
C/I:Hypersens.