All the Drug Class Drugs
Atypical Antipsychotic Agent. Iloperidone 1, 2, 4, 6, 8, 10, 12 mg. I.R.TABS: Titration pack, 60 X 1 mg, 2 mg,
4 mg, 6 mg, 8 mg,10 mg, 12 mg.
Titrat. phase - must be titr. slowly from a
low start. dose to avoid orthost.
hypotens. due to its α-adrener. block.
properties.
Recom. start. dose for 1 mg ×2/ d. Incr.
to reach the target dose range of 6-12
mg ×2/ d may be made with dly.
dosage adjust. to 2, 4, 6, 8, 10 mg ×2/ d
on days 2, 3, 4, 5, 6, and 7, respectively.
Efficacy was demonstrated with dose
range of 6 -12 mg ×2/ d.
Prescribers should be mindful of the
fact that pts. need to be titr. to an
effective dose. Thus, control of sympt.
may be delayed during the first 1 - 2
weeks of tmt. compared to some other
antipsychotic agents that do not
require similar titr. Some adverse react.
are dose-related. To minimize initial
tolerability issues, patients Preferable
to be taken with food.
Maint. tmt. - recom. mainten. dose- 12
mg/d, administ. as either 6 mg ×2/ d or
12 mg ×1/ d. Pts. should be period.
reassessed to determine the need for
maint. tmt. Max. dose - 12 mg ×2/ d.
An atypical antipsychotic agent for tmt.
schizophrenia in adults.
C/I: Known hypersensitivity.
