All the Active Ingredient Drugs
Folic Acid Analog. Pemetrexed (as diacid monohydrate) 25 mg/ml. Sol for IV inf. 1 X 4/20/34/40 ml . Dose 500 mg/m2 of body surface area (BSA) admin. as an IV inf. over 10 min. on the first day of each 21-day cycle. See lit.
In comb. with cisplatin, for the tmt. of pts with malign. pleural mesothelioma whose dis. is unresect. or who are not candid. for curatible surg. In combin. with cisplatin, for the first line tmt. of pts with locally adv. or metast. non-small cell lung canc. (NSCLC) other than predomin. squam. cell histol. As monother. for the sec. line tmt. of pts with locally adv. or metast. NSCLC other than predom. squam. cell histol. As monother. for the maint. tmt. of locally adv. or metast. NSCLC other than predom. squam. cell histol. in pts whose dis. has not progr. immediate. follow. platinum-based chemother.
C/I: Hypersens. Lact. Concom. yellow fever vacc.
