All the Active Ingredient Drugs
TNF Blocking Agent. Etanercept 25, 50 mg. VIAL (pwdr.& solvent ): 25 mg.
PRE-FILL. SYR. (sol. for inj.): 1 x 25 mg;
1 x 50 mg.
PRE-FILL. PEN (sol. for inj.): 1 x 50 mg.
Dosage must be ajust. individ.
RA: Tmt. of active RA in adult. when the
response to DMARDs include.
methotrexate (unless contraindic. ) has
been inadeq. Can be used in comb. with
methotrexate in pts. who do not respond
adeq. to methotrexate alone. Reduc.
signs&sympt. and inhibit. the progress. of
structur. damage in pts. with moder. –
sev. act. RA.
Alone or in comb. with methotrexate, has
been shown to reduce the rate of
progress. of joint damage as measure. by
X-ray and to improve. physic. funct.
Polyarticul. juven. idiopathic arthrit.:
Tmt. of active polyarticul. juven.
idiopathic arthrit. in child. & adolesc. ≥2
yrs. who have had an inadeq. respon. to,
or who have proved intoler. of,
methotrexate. The drug has not been
studi. in child. < 2 yrs.
Psor. arthrit.: Tmt. of act. & progress. psor.
arthrit. in adults when the response to
prev. DMARDs ther. has been inadeq.
The has been shown to improve. physic.
func. in pts. with psoriat. arthrit., and to
reduce the rate of progress. of peripher.
joint damage as measured by X ray in pts.
with polyarticul. symmetric. subtypes of
the dis.
Ankylos. spondyl.: Tmt. of adult. with sev.
act. ankylos. spondyl. who have had an
inadeq. response to convent. ther.
Plaque psorias.: Tmt. of adults pts. (18 yrs.
or older) with moderate to severe plaque
psor. who are candidates for system. ther.
or photother.
Ped. plaque psor. Tmt. of chron. sev.
plaque psor. in child. &adolesc. from the
age of 6 yrs. who are inadeq. control. by,
or are intoler. to, other system. ther. or
photother.
Juven. idiopat. arthrit. tmt. of polyarthrit.
(rheumat. factor posit. or neg.) and
extended oligoarthritis in child. &
adolesc. ≥2 yrs who have had an inadeq. response to, or who have proved intoler.
of, methotrexate.
Tmt. of psor. arthrit. in adolesc. ≥12 yrs.
who have had an inadeq. response to, or
who have proved intol. of, methotrexate.
Tmt. of enthesitis-related arthrit. in
adolesc. ≥ 12 yrs. who have had an
inadeq. respon. to, or who have proved
intoler. of, convent. ther.
Axial spondyloarthritis Ankylos.
spondylitis: Tmt. of adults with sev. active
ankylosing spondylitis who have had an
inadeq. response to convent. ther.
Non-radiograph. axial spondyloarthritis:
Tmt. of adult. with sev. non-radiograph.
axial spondyloarthritis with object. signs
of inflamm. as indic. by elev. CRP and MRI
evidence, who have had an inadeq.
response to NSAIDs.
C/I: Hypersens., sepsis or risk of sepsis,
Pts. with active infec. , includ. chron. or
localised infec.
