All the Active Ingredient Drugs
3rd Generation Cephalosporins. Ceftazidime as pentahydrate 1 g/vial. VIAL (Pwdr. for sol. for IV/IM inj.): 10. Dosage must be ajust. individ. accord. to the type of infec. and age of the pt.
Tmt. of the infec. listed below in adult.&child. include. neonates (from birth).
Nosocomial pneum. Broncho-pulmon. infec. in CF. Bact. mening. Chron. suppurative otitis m. Malign. otitis externa. Complic. UTI. Complic. skin & soft tissue infec. Complic. intra-abdom. infec. Bone & joint infec.Peritonitis assoc. with dialysis in pt. on CAPD. Tmt. of pts. with bacteraemia that occurs in association with, or is suspect. to be associated with, any of the infec. listed above.
May be used in the manag. of neutropenic pts. with fever that is suspect. to be due to a bact. infect.
Ceftazidime may be used in the peri-operat. prophylaxis of UTI for pts. underg. trans-urethral resect. of the prostate (TURP).
The selection of ceftazidime should take into account its antibact. spectrum, which is mainly restrict. to aerobic Gram neg. bact.
Ceftazidime should be co-admin. with other antibact. agents whenever the possible range of causive bacteria would not fall within its spect. of activity.
Consid. should be given to official guidelines on the appropr. use of antibact. agents.
C/I: Hypersens. to ceftazidime, or to any other cephalosp. antibiot.
History of severe hypersens.(e.g. anaphylac. react. to any other type of beta-lactam antibact. agent (penicillins, monobactams, carbapenems).
3rd Generation Cephalosporins. Ceftazidime (as pentahydrate) 1 g/vial, 2 g/vial. VIALS: 1 g, 2 g. 1-6 g dly. See lit. Child
and inf: 30-100 mg/kg/dly. See lit.
Tmt. of the infec. listed below in adults
and child. includ. neonates (from birth).
Nosocomial pneum.,Broncho-pulmon.
infect.in CF. Bact. mening. Chron.
suppurate. otitis med. Malign. otitis exter.
Complic.UTI. Complic. skin and soft tissue
infec. Complic. intra-abdom.infec. Bone
and joint infec. Peritonitis assoc.with
dialysis in pt. on CAPD. Tmt. of pts. with
bacteraemia that occurs in assoc. with, or
is suspected to be assoc. with, any of the
infec. listed. Manag. of neutropenic pts.
with fever that is suspected to be due to a
bacterial infec. Peri-operati. prophylaxis
of urin.tract. infec. for pts. undergoing
TURP.
C/I: Hypersens., history of severe
hypersens.(e.g. anaphylac. reac.) to any
other type of beta-lactam antibact.
agent (penicillins, monobactams,
carbapenems).
3rd Generation Cephalosporins. Ceftazidime (as Pentahydrate) 1 g, 2 g. VIAL: 1 x 1 g, 2 g. Parenteral I.V./I.M. into
large muscl. mass. Adults: 1-6 g dly
every 8 or 12 hrs. Most infects: 1 g 8
hrly or 2 g 12 hrly. Urin. tract and less
severe infects: 500 mg or 1 g 12 hrly.
Immunocompromised pts., neutropen:
2 g 8 hrly or 3 g 12 hrly. Proph. in
prostat. surg: 1 g at anesthes. Possible
2nd dose on removal of catheter.
Elderly: Max. dly dose: 3 g. Cystic
fibrosis: Adults with pseudonom. lung
infects: 100-150 mg/kg/day in 3 div.
doses. See lit. Inf. and child: Over 2
mths: 30-100 mg/kg/day in 2-3 div.
doses. Up to 150 mg/kg/day (max: 6 g/
day) in 3 div. doses to infect.
immunocompromised/fibrocyt. child,
child with meningit. Neonates and child up to 2 mths: 25-60 mg/kg/day in
2 div. doses proven effect. Impaired
ren. funct: Reduce dose. See lit. Ren.
impair: See lit.
Bact. infects. due to suscept. microorgans.
C/I: Hypersens.
3rd Generation Cephalosporins. Avibactam 0.5 g, Ceftazidime (as Pentahydrate) 2 g. Vials: powder for IV sol. for inf. X 10
Dosage to be adj. as per infect. type, ptt. age and condition
In adlts and paed. ptts. aged 3 mo. and older for the tmt. of:
Complic. intra-abdominal infect. (cIAI), used in combin. with Metronidazole
Complic. urinary tract infect. (cUTI), incl. pyelonephritis
Hosp.-acquired pneumonia (HAP), incl. ventilator assoc. pneumonia (VAP)
Tmt. of adlt. ptts. with bacteraemia that occurs in assoc. with, or is susp. to be assoc. with, any of the infect. listed above.
Also indic. for the tmt. of infect. due to aerobic Gram-negat. organisms in adlts. and paed. pts. aged 3 mo. and older with limit. tmt. options.
Consider official guid. on the appropr. use of antibact. agents.
C/I: Hypersens. to any cephalosporin and any other type of beta-lactam antibiotics.
