All the Therapeutic System Drugs
Androgen. Danazol 200 mg. CAPS: 60.
Fertile females: Start during
menstruat. on 1 st day. Childbear. age:
Use non. hormon. contracept. through
course of tmt. Endometrios: 200-800
mg dly. for 3-6 mths. Incr. if bleed.
persists aft. 2 mths. to 800 mg/day in
severe cases. Proph. heredit.
angioedema: Initial: 200 mg 2-3 x dly.
Maint: Decr. initial dose by 50% or less
at intervals of 1-3 mths. or longer.
Prevent. tmt.: Continuous effective
lowest dose. Elderly and child: Not
recommend.
Endometriosis amenable
to hormonal management, hereditary
angio-edema.
C/I: Preg., lact., markedly impair. hep.,
renal or card. func. Porphyria, active
thrombosis or thromboemb. dis., hist. of
such events. Androgen depend. tumor,
undiagnosed abnor. gen. bleed.
GnRH Agonist. Triptorelin Acetate 0.1 mg/ml. PFS: 0.1 mg/ml. See lit.
Lowers sexual hormones, precocious
puberty, endometriosis,
uterusleiomyoma, IVF.
GnRH Agonist. Triptorelin Acetate 3.75 mg. MICROCAPSULES C.R: 1 kit x 3.75 mg. 1
I.M. inject. mthly. See lit.
Lowers sexual hormones, precocious
puberty, endometriosis,
uterusleiomyoma, IVF.
Progestogen. Dydrogesterone 10 mg. FC Tabs: 42.
Dosage: see lit.
Cases where progest. suppl. is needed.
C/I: Hypersens. Vag. bleeding, where the cause has not been establ. Tmt. for luteal supp. as part of an Assisted Reproductive Technology (ART) tmt. should be discont. upon diagn. of abortion or miscarr. Pres. of sev. liver disord., or sev. liver disord. in med. hist. until liver funct. values have returned to normal. C/I for use of oestrogens in combin. with progestogens such as dydrogesterone in comb. ther. Known or susp. sex horm. dep. malign.
GnRH Agonist. Leuprorelin Acetate 11.25 mg. PREFILLED DUAL CHAMBER SYRINGE
(PDS): 1 x 3.75 mg, 11.25 mg/vial.
3.75 mg mthly.; 11.25 mg/vial: every 3
mths. Both I.M. or S.C. See lit.
Prostat. carcinoma, endometrios., uterine
fibroids (for up to 6 mths.). Tmt breast
cancer in pre/peri-menopaus. women in
whom hormone ther. is specified.
C/I: Hypersens. to the product or similar
nonapeptides; Anaphylaxis; Undiagn.
abnorm. vag. bleed.; Pregn.; Lact.
Additionaly, the 11.25 mg formulation:
pts follow. an orchiectomy.
GnRH Agonist. Leuprorelin Acetate 3.75 mg. PREFILLED DUAL CHAMBER SYRINGE
(PDS): 1 x 3.75 mg, 11.25 mg/vial.
3.75 mg mthly.; 11.25 mg/vial: every 3
mths. Both I.M. or S.C. See lit.
Prostat. carcinoma, endometrios., uterine
fibroids (for up to 6 mths.). Tmt breast
cancer in pre/peri-menopaus. women in
whom hormone ther. is specified.
C/I: Hypersens. to the product or similar
nonapeptides; Anaphylaxis; Undiagn.
abnorm. vag. bleed.; Pregn.; Lact.
Additionaly, the 11.25 mg formulation:
pts follow. an orchiectomy.
