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    9 Drugs classified under this therapeutic system


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    Cabotrim 0.5
    Trima
    RX
    partial basket chart
    Cabotrim 0.5

    Domapine Agonist. Cabergoline 0.5 mg.
    TABS: 2, 8. Take with meals. Dose: See
    lit.
    Tmt. dysfuncts., assoc. with
    hyperprolactinem., incl. amenorrh.,
    oligomenorrh., anovulat., galactorrh. In
    pts. with prolactin-secret. pituitary
    adenomas (micro/macro) idiopath.
    hyperprolactinem., empty sella syndr.
    with assoc. hyperprolactinem.
    C/I: Hypersens., any ergot alkaloid,
    uncontrolled hypertens.

    Dostinex
    Pfizer
    RX
    partial basket chart
    Dostinex

    Domapine Agonist. Cabergoline 0.5 mg.
    TABS: 2, 8. 1 tab. wkly. in 1 or 2 doses. If
    necess. incr. grad. by 1 tab wkly at
    mthly intervals. Maint: 1 mg wkly. with
    ranges from 0.25 mg-2 mg. Up to 4.5
    mg wkly. have been used.
    TABS: 2. Inhibit. lact: Admin. during 1st
    day (24 hrs.) post-partum: 1 mg (2 x 0.5
    mg tabs) as single dose. Suppress. estab. lact: 0.25 mg (1/2 0.5 mg tab)
    every 12 hrs. for 2 days (1 mg total
    dose).
    Hyperprolactinem. disords, dysfuncts.
    assoc. with hyperprolactinem., prolactinsecret.
    pituitary adenomas, idiopath.
    hyperprolactinem., empty sella synd.
    with assoc. hyperprolactinem., inhibit.,
    suppress lact.
    C/I: Hypersens. to ergot alkaloid,
    uncontrolled hypertens.

    Norprolac (Starter Pack)
    Ferring Pharmaceuticals
    RX
    partial basket chart
    Norprolac (Starter Pack)

    Domapine Agonist. Quinagolide HCl 0.025, 0.05 mg.
    TABS: 3 + 3 x 25 μg, 50 μg (starter pack). 25 μg/day for first 3 days, foll. by 50 μg/day for 3 days. From day 7: 75 μg/day. See lit.
    2nd line tmt. hyperprolactinem.
    (idiotpath./due to prolactin secret. micro/
    macroadenoma) and clin. maninfests.
    (galactorrh., oligomenrrh., infertil.,
    reduced libido).

    Norprolac 75, 150 mcg
    Ferring Pharmaceuticals
    RX
    partial basket chart
    Norprolac 75, 150 mcg

    Domapine Agonist. Quinagolide HCl 0.075, 0.15 mg.
    TABS: 3 + 3 x 25 μg, 50 μg (starter pack);
    30 x 75 μg, 150 μg. 25 μg/day for first 3
    days, foll. by 50 μg/day for 3 days. From
    day 7: 75 μg/day. See lit.
    2nd line tmt. hyperprolactinem.
    (idiotpath./due to prolactin secret. micro/
    macroadenoma) and clin. manifests.
    (galactorrh., oligomenrrh., infertil.,
    reduced libido).

    Primolut-Nor
    Bayer
    RX
    full basket chart
    Primolut-Nor

    Progestogen. Norethisterone Acetate 5 mg.
    TABS: 20. See lit.
    Dysfunct. bleed., primary and second.
    amenorrh., premenstrual syndr.,
    mastopathy, uterine hypoplasia, timing of
    menstruation, endometriosis.
    C/I: Pregn., severe disturb. liver funct.,
    Dubin-Johnson syndr., Rotor syndr.,
    past, present liver tumors, history
    jaundice, severe prurit., herpes during
    pregn., thromboembol. processes

    Provera 5 mg
    Pfizer
    RX
    full basket chart
    Provera 5 mg

    Progestogen. Medroxyprogesterone Acetate 5 mg.
    TABS.: 100, 24. Endometriosis: Oral MPA 10 mg three times per day for 90 consec. days, begin. on the 1ST d of the menstrual cycle.
    Menopaus. Vasomotor Sympt.: Oral MPA 10-20 mg/d given continuous.
    Diagn. of prim. and secon. Amenorrhea: Oral MPA 2.5-10 mg/d for 5-10 d.
    Tmt. of second. Amenorrhea: Oral MPA 2.5- 10 mg dly. for 5-10 days, for 3 consecut. cycles. In pts. with hypotrophy of the endometrium, estrogens should be used concomit. with MPA ther.
    Dysfunctional (Anovulatory) Uterine Bleed.: Oral MPA 2.5 to 10 mg/ d for 5–10 d for 2-3 cycles and then discont. to see if the dysfunct. has regressed. If bleed. occurs from a poorly proliferative endometrium, estrogens should be used concomit. with MPA ther.
    Opposition of endometrial effects of estrogen in menopaus. women being treated with estrogen (Hormone Therapy [HT]): For women taking 0.625 mg of conjugated estrogen or an equivalent dly. dose of another estrogen, MPA can be given in one of two regimens:
    Continuous regimen of MPA- Oral MPA 2.5 to 5.0 mg dly.
    Sequent. regimen of MPA- Oral MPA 5 to 10 mg dly. for 10- 14 consecut. d. of a 28-d or monthly cycle.
    Indicated for cases requiring progesterone supplem.
    C/I: Hypersens. Known/suspect. preg. Known, past or suspect. breast cancer; Previous idiopathic or current venous thromboembolism (DVT, PE). Active/recent arterial thromboembolic dis. (e.g angina, MI); Acute liver dis., or a history of liver dis. as long as liver funct. tests have failed to return to normal. Porphyria.


    Other therapeutic systems under Obstetrics and Gynecology

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