Who are we?
Gilead Sciences, Inc. is a research-based biopharmaceutical company that discovers, develops and commercializes innovative medicines in areas of unmet medical need. We strive to transform and simplify care for people with life-threatening illnesses around the world. Gilead’s portfolio of products and pipeline of investigational drugs includes treatments for HIV/AIDS, liver diseases, cancer, inflammatory and respiratory diseases, and cardiovascular conditions.
Our portfolio of marketed products includes a number of category firsts, including complete treatment regimens for HIV infection available in a once-daily single pill and the first oral antiretroviral pill available to reduce the risk of acquiring HIV infection in certain high-risk adults.
Drugs Disributed by Gilead Sciences Israel Ltd
Antifungal. Amphotericin B 50 mg/vial. VIALS: 10. 1 mg/kg bdy. wt. dly. incr.
step-wise as reqd. I.V. infus. over 30-60
mins. See lit.
Severe system. and/or deep mycoses,
where toxicity (partic. nephrotox.)
precludes use of convent. ther., syst. fung.
infects. in immunocomp. pts., prim. ther.
visceral leishman. in immunocompetent
pts., immuno-compromised pts. e.g. HIV pos.
C/I: Hypersens.
Antiretrovirals. Bictegravir 50 mg, Emtricitabine 200 mg, Tenofovir Alafenamide 25 mg. FC tabs: 30
One tab. once /d. See lit.
Tmt. of adlts infect with human immunodefic. virus-1
(HIV-1) w/o present or past evid. of viral resist. to the integrase inhib. class, emtricitabine or tenofovir
C/I:Hypersens.Co-administr. with rifampicin and St. John’s wort (Hypericum perforatum
Monobactams. Aztreonam 75 mg. VIAL (pwdr. & solven. for nebuliser sol.): 2 ml ×75 mg. Pts. should use a bronchodilator before each dose of Aztreonam. Short act. bronchodilators can be taken between 15 min. and 4 hrs. and long act. bronchodilat. can be taken between 30 min. and 12 hrs. prior to each dose of Aztreonam. For pts. taking multiple inhal. therap., the recomm. order of admin. is as follows: 1. broncho-dilator 2. mucolytics 3. and lastly, Aztreonam. Adult. & child. 6 yrs and old.: 75 mg ×3/d per 24 hrs. for 28 d. should be taken at least 4 hrs. apart. May be taken in repeat. cycles of 28 d. on ther. follow. by 28 d. off Aztreonam ther. See lit.
Indic. for the suppres. ther. of chron. pulmon. infect. due to P. Aeruginosa in pts. with CF aged 6 yrs. and older. Consid. should be given to official guidance on the appropriate use of antibact. agents.
C/I: Hypersens.
Anti HIV, Nucleoside and Nucleotide Reverse Transcriptase Inhibitors. Emtricitabine 200 mg, Tenofovir Alafenamide 10 mg, 25 mg. F.C. TABS.:30. Dosage must be ajust. individ.
Indicated in comb. with other antiretrovir. agents for the tmt. of adult. and adolesc. (aged 12 yrs. and older with bdy. wt. at least 35 kg) infect. with human immunodeficiency virus type 1 (HIV-1).
C/I: Hypersens.
Antivirals. Sofosbuvir 400 mg, Velpatasvir 100 mg. F.C. TABS.: 28. One tab., taken oral., once dly. with or without food. See lit.
Treatment of chronic hepatitis C virus
(HCV) infection in adults.
C/I: Hypersens.
Meds. that are strong P-gp and/or strong P450 CYP induc.(carbamazepine, phenobarbital, phenytoin, rifampicin, rifabutin and St. John’s wort).
Antiretrovirals. Emtricitabine 200 mg, Elvitegravir 150 mg, Cobicistat 150 mg. FILM COAT. TABS.:30.
Adult., paed. 6 yrs. and older, wt. at least 25 kg: 1 tab. ×1/d with food. If the pt. misses a dose within 18 hrs. of the time it is usual. taken, the pt. should take the drug with food as soon as possible and resume the normal dosing schedule. If a pt. misses a dose by more than 18 hrs., the pt. should not take the missed dose and simply resume the usual dosing schedule. If the pt. vomit. within 1 h of taking the drug another tab. should be taken.
Tmt. of adults & adolesc. (aged 12 yrs.& older with bdy. wt. at least 35 kg) and In child. aged 6 yrs. & older with bdy wt at least 25 kg for whom alternative regimens are unsuitable due to toxicities infect. with HIV 1 without any known mutations assoc. with resist. to the integrase inhib. class, emtricitabine or tenofovir.
C/I: Hypersens. Co-admin. with: Alfuzosin, amiodarone, quinidine, dihydroergotamine, ergometrine, ergotamine, cisapride, lovastatin, simvastatin, lomitapide, pimozide, lurasidone, sildenafil for tmt. of pulmon. arter. Hypertens., midazolam, triazolam, carbamazepine, phenobarbital, phenytoin, rifampicin, St. John’s wort (Hyperic. perfora.), dabigatran.
