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Adults: The recommended dose is one tablet taken orally once daily. The tablet should be swallowed whole, on empty stomach not crushed, chewed or halved.
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Indicated for use alone as a complete regimen or in combination with other antiretroviral agents for the treatment of HIV-1 infection in adults.
Hypersensitivity to an active substance or to any of its excipients.
Patients with severe liver disease.
Patients with cardiac disorders e.g.: QT prolongation, Torsades de Pointes.
Patient with family history of cardiac disorders.
Patients with hypokalemia, hypomagnesemia.
Concomitant use with astemizole, terfenadine− bepridil, cisapride elbasvir/grazoprevir, ergot alkaloids (e.g. ergotamine, dihydroergotamine, ergonovine and methylergonovine) midazolam or triazolam, pimozide, imipramine, amitriptyline or clomipramine, hypericum perforatum (st. john’s wort) voriconazole, flecainide, metoprolol, macrolides, fluoroquinolones, imidazole, anti-fungal triazole, certain anti-malarial medicines, methadone.