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5 ml x 20 mg/ml
15 ml x 20 mg/ml
25 ml x 20 mg/ml
Dosage must be adjusted individually.
For the treatment of patients with metastatic colorectal cancer:
In combination with 5-fluorouracil and folinic acid in patients without prior chemotherapy for metastatic disease.
As a single agent in patients who have failed an established 5-fluorouracil containing treatment regimen.
For the treatment of patients with small cell lung cancer.
For the treatment of patients with gastric cancer.
Hypersensitivity to the active substance or to any of the excipients.
Chronic inflammatory bowel disease and/or bowel obstruction.
Pregnancy and lactation.
Bilirubin > 3 times the ULN.
Severe bone marrow failure.
WHO performance status > 2.
Concomitant use with St John’s Wort.
Pregnancy and Lactation
Contraindicated in pregnancy and lactation.