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    / Dexcel

    Active Ingredient
    Senna 150-220 mg

    Status in Israel

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    Presentation Basket Yarpa Pharmasoft



    not in the basket chart 79115 2047

    Related information


    The maximum daily intake must not exceed 30 mg of hydroxyanthracene derivatives; this corresponds to 1 coated tablet.
    This results in the following dosages: Adults and adolescents over 12 years of age take 1 coated tablet 1 x daily before retiring. The individually correct dose is the smallest one necessary to produce loosely formed stools. The effect sets in after 8-12 hours.




    Must not be taken in cases of allergy to Tinnevelly senna pods or to one of the other constituents of the medicinal product, in cases of ileus, appendicitis, chronic inflammatory intestinal diseases such as for example Crohn’s disease, colitis ulcerosa, in cases of abdominal pains of unknown genesis, in cases of severe dehydration with water and salt loss, by children under 12 years of age.
    It is drawn to the attention of the patient in the package information sheet that a doctor should be consulted before taking the preparation at the same time as cardiac glycosides, antiarrhythmic drugs, diuretics, cortisone and similar substances to cortisone or liquorice root.

    Special Precautions

    The use of stimulating laxatives for more than a short-term application may lead to increased sluggishness of the bowels. The preparation should only be taken if the constipation cannot be remedied by a change of diet or by preparations that act through swelling substances.
    Note: Incontinent adults who take Tablets should avoid lengthy skin contact with the faeces by changing the sanitary towel.

    Side Effects

    Very Rarely, spasmodic gastro-intestinal disorders may occur. In such cases, it is necessary to reduce the dose. Very rarely it is possible for hypersensitivity reactions (itching, urticaria, local or generalised exanthemas) to occur. In the course of the treatment, a harmless reddening of the urine may occur. In the case of chronic use/abuse of the preparation this could lead to disturbances of the water balance or the electrolyte metabolism. Diarrhea may occur and may lead in particular to potassium losses. The loss of potassium may in turn lead to disturbances of the cardiac function and to muscular weakness, especially if cardiac glycosides, diuretics and adrenal cortical steroids are taken at the same time. Chronic use may be accompanied by albuminuria and haematuria. Furthermore, a pigmentation of the intestinal mucosa (pseudomelanosis coil) may occur, which however is harmless and usually recedes after discontinuation of the drug.
    The following is drawn to the attention of the patient in the package information sheet: If side effects occur, it is necessary to reduce the dose or possibly to discontinue the use of the medicinal product.
    At the first signs of a hypersensitivity reaction, the pharmaceutical product must no longer be taken. If necessary go and see your doctor so that he can treat the side effects that have occurred.

    Drug interactions

    The chronic use/abuse of the preparation could lead to a strengthening of the cardiac glycoside effect due to potassium losses as well as to an influence on the effect of antiarrhythmic drugs. Potassium losses may be amplified through a combination of the preparation with diuretics, adrenal cortical steroids or liquorice root.

    Pregnancy and Lactation

    This drug should only be taken during the first three months of pregnancy if the constipation cannot be remedied by a change of diet or by preparations that act through swelling substances.
    Note: Degradation products of the senna pods with a laxative effect such as rhein find their way into the mother’s milk in small quantities. No laxative effect has been observed in constipated infants.


    In the case of an inadvertent or intentional overdose, painful spasms of the intestines and severe diarrhea may occur, leading to water and salt losses as well as possible severe gastrointestinal complaints.
    In the directions for use, the attention of the patients is drawn to the following: If an overdose has been taken, please notify a doctor immediately. He will decide what countermeasures (e.g. an infusion of liquid and salts) may be necessary.

    Important notes

    Contains lactose, glucose and sucrose.
    For full details see prescribing information.

    Roha Arzneimittel
    Licence holder