All the Active Ingredient Drugs
Cytotoxic Antibiotic. Mitomycin C 10 mg. VIALS (pwdr. for sol. for inj.): 5 x 10 mg.
Intermittent admin.: Usual. (adults), 4
to 6mg (potency)/d, IV once/twice a
Admin. on consecutive days: Usual.
(adults), 2mg (potency)/d IV every day.
Intermittent massive admin.: Usual.
(adults), 10- 30mg (potency)/d IV every
1- 3 wks. or at longer interv.
Concurrent use with other antineopl.
agents: Usual. (adults), 2-4mg
(potency)/d once/ twice a week in
comb.with other antineopl. agents. Pts. with bladder tumor: prophylact.
use against recurrence, 4- 10mg
(potency) of usual. admin. IV once
every day/every other day. For therap.
use, 10- 40mg (potency)/d
intravesically once a day. The dosage
may be adjust. depend. on the age and
sympt. of the pt. See Lit.
Remis.of subject. and object. sympt. assoc.
with the follow. dis.: Chron.lymphoc.
leukemia, chronic myelocytic leukemia,
gastric canc. colorectal canc., lung canc.,
pancreatic canc., liver canc., cervix canc.,
canc. of endometrium, breast canc., head
and neck tumor and bladder tumor. See
C/I: Pts. with a history of serious
hypersens.or idiosyncratic react. to any
of the compon.of the product.
Thrombocytopenia, coagul. disorders
and incr.bleed. tendency. See Lit.